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Conjugated Lionoleic Acid |
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Conjugated Linoleic Acid
Conjugated Linoleic Acid (CLA) is an omega-6 fatty acid that is found in corn oil, safflower oil, sunflower oil, canola oil, nuts, seeds, beef and dairy products. The balance between the omega-6 and omega-3 is vital to overall health and disease prevention. Therefore, Linoleic acid is essential for the body and should be incorporated in all diets to prevent a deficiency. How This Supplement Works in Your Body:
Where This Supplement is Found:
How to Use:
Cautions:
Consult your doctor if you are:
Pregnancy:
Infants and Children: Storage:
Safe dosage:
Toxicity:
Side Effects:
Health Benefits of Conjugated Linoleic Acid Many people are taking CLA as an expensive supplement for the benefits described below. But wouldn't it make much more sense to get it for free in your food? There is a new reason why it may be beneficial to allow cows to graze on pasture. That reason involves a compound called conjugated linoleic acid (CLA). CLA is a fatty acid found in beef and dairy fats. Scientific interest in CLA was stimulated in 1988 when a University of Wisconsin researcher discovered its cancer-fighting properties in a study of rats fed fried hamburger. CLA cannot be produced by the human body, but it can be obtained through foods such as whole milk, butter, beef, and lamb. "The interesting thing is that dairy cattle that graze produce higher amounts of CLA in their milk than those which receive conserved feed, such as grain, hay, and silage," says Agricultural Research dairy scientist Larry Satter. This is true even when the nongrazers eat pasture grass conserved as hay. Satter, who is based at the Dairy Forage Research Center in Madison, Wisconsin, conducted a study comparing the amount of CLA in milk from cows grazing on pasture to the amount from cows fed hay or silage. His findings: Pasture-grazed cows had 500% more CLA in their milk than those fed silage. Larry Satter is at the USDA-ARS U.S. Dairy Forage Research Center, 1950 Linden Lane, University of Wisconsin, Madison, WI 53706; phone (608) 264-5353, fax (608) 264-5147. CLA may be one of the most potent cancer-fighting substances in our diet. In animal studies, as little as one half of one percent CLA in the diet has reduced tumor burden by more than 50 percent. CLA has also been shown to reduce body fat in people who are overweight. A double-blind, randomized, placebo-controlled study, published in the December 2000 issue of the Journal of Nutrition found that CLA reduces fat and preserves muscle tissue. According to the research project manager, an average reduction of six pounds of body fat was found in the group that took CLA, compared to a placebo group. The study found that approximately 3.4 grams of CLA per day is the level needed to obtain the beneficial effects of CLA on body fat. Dr. Michael Pariza, who conducted research on CLA with the University of Wisconsin-Madison, reported in August 2000 to the American Chemical Society that "It doesn't make a big fat cell get little. What it rather does is keep a little fat cell from getting big." Pariza's research did not find weight loss in his group of 71 overweight people, but what he did find was that when the dieters stopped dieting, and gained back weight, those taking CLA "were more likely to gain muscle and not fat.'' In a separate study conducted at Purdue University in Indiana, CLA was found to improve insulin levels in about two-thirds of diabetic patients, and moderately reduced the blood glucose level and triglyceride levels. CLA has been the subject of a variety of research in the past several years, and findings also suggest that some of the other benefits of CLA include the following:
If you're interested in taking CLA to help with weight loss, keep in mind that it's not a magic, and you will need to start a program of diet and exercise in order to successfully lose weight and keep it off. Conjugated linoleic acid (CLA) is a mixture of positional and geometric isomers of linoleic acid, which is found preferentially in dairy products and meat. Preliminary studies indicate that CLA is a powerful anticancer in the rat breast tumor model with an effective range of 0.1-1% in the diet. Conjugated linoleic acid is unique because it is present in food from animal sources, and its anticancer efficacy is expressed at concentrations close to human consumption levels. Conjugated linoleic acid and atherosclerosis in rabbits Lee K.N.; Kritchevsky D.; Pariza M.W. Food Research Institute, Dept. Food Microbiology/Toxicology, University of Wisconsin-Madison, 1925 Willow Drive, Madison, WI 53706 USA Atherosclerosis (Ireland), 1994, 108/1 (19-25)
Margarine and Trans Fats Up Heart Attack Risk\ Heart attack victims have significantly less omega-3 fatty acids, and more trans fats, linoleic acid and alpha-linolenic acid in their adipose (fat) tissue.
Adipose tissue composition of the following fatty acids were all significantly lower in heart attack victims than the control group:
Adipose tissue composition of the following fatty acids were all significantly higher in heart attack victims than the control group:
The authors note that the tissue concentrations of trans fatty acids, linoleic acid and alpha-linolenic acid in adipose tissue were strongly correlated, which indicates a common source, most likely margarine. The authors conclude that intake of omega-3 fatty acids is inversely associated with risk of heart attack, whereas the intake of trans fats, linoleic and alpha-linolenic acid are associated with increased risk. Although not certain of the cause of this link, the authors note that " ... the increased risk may be connected to trans fatty acids or to some other factor associated with margarine consumption." European Journal of Clinical Nutrition August, 2000;54:618-625.
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