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I am a Mexican naturopathic Dr, with a postgraduate specialty in acupuncture and phytotherapy, and I have been also practicing ozone therapy for three years now.

One of my patients, carrier of chronic viral illnesses (HIV and Hep B) recently showed some decrease in the CD8 and CD4 count. For my ozone therapy training, I know that o3 has a profound effect on the immune system, observing different effects according to the specific dosage.

Hence, I was thought that o3 doses between 10 and 20 mcg (gammas) are stimulant to the immune system, doses between 20 and 40 mcg (gammas) are modulatory (usefull in autoimmune diseases for example) and doses between 40 and 80 mcg are microbicidal but can also be immuno-supressive.

My patient was receiving a daily cumulative dose of over 23,000 mcg, and his symptoms were compatible with over-oxidation (tiredness and malaise mainly).

My question to you is wether or not you have observed a similar effect on patients with such a high dose of ozone. For now, I have reduced the cumulative dose of o3 to 3000 mcg/ml (gammas).
I look forward to your answer, and thanks for sharing knowledge and experience.

Dear Dr.,

I think there is a confusion between concentration and its
effects, and total ozone administered.

There is ug/ml or mcg/ml (micrograms per millilter) (also called gamma) which is a concentration measurement.

Then, there is total volume, measured as mcg or ug (micrograms). (It is not gamma, which is not a volume measurement).

[I have taken "gamma" out of your letter where it was inappropriate,
in order to avoid confusion to readers.]

The highest immune response is seen at around the 48 ug/ml mark,
as shown in Drs. Rilling and Viebahn's book (The Use of Ozone in Medicine, 1987), where they reprint several of Prof. Bocci's charts
on immune system markers that he tested. This concentration of 48 ug/ml is the most common concentration employed by researchers around the world, when they perform their medical ozone tests.

Immune suppression does not become a factor until concentrations above 70 ug/ml (gamma) are applied.

Now, on to total ozone administered.

A total ozone volume of 23,000 mcg (ug) is not excessive.
It depends on the method of application. There is no way to get that kind of amount in via injection. It would have to be by insufflation.

A 30 minute session of insufflation at 1/32 l/m and 30 ug/ml concentration results in an administration of 30,000 ug. This is a standard protocol with vaginal insufflation, and rectal insufflation (for people able to go that long).

The symptoms of tiredness and malaise are what we call the healing crisis brought on by detoxification, and a liver that is overburdened. It is not over-oxidation, it is PROPER oxidation.
The healing crisis can be ameliorated by improving the cleanliness of the liver, by a series of liver cleanses.

We are actually looking to induce this healing crisis. We are much more alarmed when we continue to pour in large volumes of ozone day after day and do NOT see the healing crisis. We start then to look for psychological factors causing the person's immune system to stay "off" even with this powerful stimulus. That is where EFT comes in.

In water purification by ozone (employed by over 3000 municipalities worldwide, including all the great cities) the concentration of ozone is 1 ug/ml. This is sufficient to destroy bacteria, viruses, fungi, spores, cysts, etc. So the idea that we need higher concentrations is related to the problem of getting ozone in contact with the target in the body's myriad 'pouches' (cells) which are not 'open' like water is.

Therefore, the pigeonholing of ozone application by concentration is an attempt to view ozone as a drug, and narrowly confine its
application by dose.

All such efforts are doomed to fail, as they do not recognize that ozone therapy consists of administering electricity to the body. The oxygen is just the carrier. There is no recognizance of this fact in modern ozone theory, because there is no modern teaching of electrotherapies. Everything is done on a chemical basis, even though a close reading of the university medical texts shows that the motive force is, indeed, the electron, and chemical effects are RESULTS of that.

Until that basic fact of ozone physics is understood, we will continue to have a largely allopathic approach driven by symptomolgy
rather than a naturopathic approach that looks at first causes, and encourages the healing actions of the body.

Best of Health!
Dr. Saul Pressman