A5: Dear Dr Hedyat,
In the case of lung diseases, such as berylliosis or sarcoidosis, you should always suspect chronic metal exposure as a possible cause of the granulomatous diseases. The same can be true for lung pulmonary disease.
In the case of berylliosis, Be-specific lymphocyte stimulation test, LST is a golden standard for the diagnosis and if the patients were found positive in the test, workers are labelled as "allergic" and relocated to beryllium-free environment. In sarcoidosis, the T-cell lymphocyte reactivity has been described as well for beryllium. We have studied quite a few of patients with sarcoidosis who reacted to metal components of their dental fillings, especially to gold, mercury and palladium in so called LTT_MELISA test (
http://www.melisa.org). We have one patient cured from sarcoidosis simply by replacement of her sensitizing dental metals.
I would suggest that your patient will complete a Questionnaire,which is attached, we can then recommend the laboratory to use and what to test for. The best is scan the document or fax it to the fax below.
Recently, we have been informed that titanium (suspension Ti02) is accumulated in lungs and liver and is highly thrombogenic material! We are all exposed to titanium through various sources but the most important one is be a white colour pigment, E 171 added to foods, and medicaments.
Kind regards
Vera Stejskal
Associated Professor of Immunology
University of Stockholm, Sweden and
1st Medical Faculty, Charles University, Prague, Czech Republic Tel & fax: +46 8753 2322
http://www.melisa.org