Q: There's been a few positive articles about DCA (dichloroacetate) for cancer, but clinical guidelines are hard to come by and there is some risk of causing a toxic neuropathy. The best I could find is and article on using it for congenital lactic acidosis in kids (25-50mg/kg/d oral) with only a "modest" effect on nerve conduction: http://pediatrics.aappublications.org/cgi/content/full/117/5/1519
However, this study found peripheral neurpathy in all patients (adults) who took 25mg/kg/day (route unspecified, but presumably oral) in less then 2 years: http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16476929
Does anyone have any experience with using it, doses, route of administration, etc they can share?
Dr. Malcolm Sickels MD
210 Little Lake Drive, Suite 10
Ann Arbor, MI 48103http://drsickels.com