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Q: Does anyone have any experience with pulmonary hypertension and chelation? Any other suggestions for treatment?
Thank you,

Robban A. Sica, MD

A1: yes chelation worked in 2 very ill patients of mine, use low dose EDTA definitely not 3 hour Rx
D.Wittel MD Kelowna BC chelationbc.com

A2: For Pulmonary Hypertension please research EXSELSA, a mixture of DMSO and MSM. For IV administration. Sorry all my info is at the office and I'm doing email at home. Call me weekday mornings for "how to order info".
Gordon josephs MD(H)

A3: Of interest - I sent my 63 year sister with dx of pulmonary hypertension, sleep apnea and leg edema for a trans-esophageal echocardiogram. Prior std echo was negative as well as angiogram except showing pulm hypertension. Turned out she had a patent foramen ovale - there are two guys that can fix this without open surgery - one in Omaha NE. Turns out fixing it reversed her other problems. Regular "invasive cardiologist" can do trans-esophageal echo. Realize this is not what you were looking for but felt it was worth mentioning since risk of PTO is right to left shunt and sometimes results in CVA's or TIA's since emobli present in all of us from time to time are free to pass from right to left side and directly north to the brain.

Gayle Madeleine Randall MD
Integrative and Internal Medicine

A4: If clinically there is a condition of fluid retention and likely an associated inter-relation with the Kidney system which if assaulted by toxic metals then a functional disruption of tissue results and could reflect with HBP. The remedy apart from chelation would be glonoin to improve circulation of the capillary bed, and one of several herbal constructs from the pharm. of TCM that would promote the K/L function and resolve phlegm retention.

A5: There is research indicating sildenafil has been helpful in this situation:

Circulation. 2007 Jan 2;115(1):59-66. Epub 2006 Dec 18. Links

Sildenafil improves exercise hemodynamics and oxygen uptake in patients with systolic heart failure.
Lewis GD, Lachmann J, Camuso J, Lepore JJ, Shin J, Martinovic ME, Systrom DM, Bloch KD, Semigran MJ.
Cardiology Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

BACKGROUND: Heart failure (HF) is frequently associated with dysregulation of nitric oxide-mediated pulmonary vascular tone. Sildenafil, a type 5 phosphodiesterase inhibitor, lowers pulmonary vascular resistance in pulmonary hypertension by augmenting intracellular levels of the nitric oxide second messenger, cyclic GMP. We tested the hypothesis that a single oral dose of sildenafil (50 mg) would improve exercise capacity and exercise hemodynamics in patients with chronic systolic HF through pulmonary vasodilation.
METHODS AND RESULTS: Thirteen patients with New York Heart Association class III HF underwent assessment of right heart hemodynamics, gas exchange, and first-pass radionuclide ventriculography at rest and with cycle ergometry before and 60 minutes after administration of 50 mg of oral sildenafil. Sildenafil reduced resting pulmonary arterial pressure, systemic vascular resistance, and pulmonary vascular resistance, and increased resting and exercise cardiac index (P<0.05 for all) without altering mean arterial pressure, heart rate, or pulmonary capillary wedge pressure. Sildenafil reduced exercise pulmonary arterial pressure, pulmonary vascular resistance, and pulmonary vascular resistance/systemic vascular resistance ratio, which indicates a selective pulmonary vasodilator effect with exercise. Peak VO2 increased (15+/-9%) and ventilatory response to CO2 output (VE/VCO2 slope) decreased (16+/-5%) after sildenafil treatment. Improvements in right heart hemodynamics and exercise capacity were confined to patients with secondary pulmonary hypertension (rest pulmonary arterial pressure >25 mm Hg).
CONCLUSIONS: The present study shows that in patients with systolic HF, type 5 phosphodiesterase inhibition with sildenafil improves peak VO2, reduces VE/VCO2 slope, and acts as a selective pulmonary vasodilator during rest and exercise in patients with HF and pulmonary hypertension.

PMID: 17179022 [PubMed - indexed for MEDLINE]

more information about chelation, chelator, oral chelation scam, intravenous chelation therapy, bio chelat, beyond chelation improved, kelation therapy http://www.dreddyclinic.com/integrated_med/chelation.php

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